WebJan 12, 2007 · Exposure of macrophages to bacterial products such as lipopolysaccharide (LPS) results in activation of the NF-κB transcription factor, which orchestrates a gene expression programme that underpins the macrophage-dependent immune response. These changes include the induction or repression of a wide range of genes that regulate … WebOct 5, 2024 · a Heatmap showing the top IER2-induced genes in B16-ind-IER2 #51 cells treated either with DMSO or RSL (3 × 0.5 μM) assessed using a Mouse Cancer Inflammation and Immunity Crosstalk PCR Array. b...
miR‐365 secreted from M2 Macrophage‐derived …
WebDusp2 was suppressed by salubrinal in LPS-activated macrophages as well as PMA/ionomycin-activated T lymphocytes and mast cells. Furthermore, a partial silencing of Dusp2 downregulated IL1β and Cox2, and the inflammatory signs of CAIA mice were significantly suppressed by salubrinal. WebMar 8, 2024 · B-cell translocation gene 2 (BTG2), a member of the anti-proliferative BTG/TOB gene family, 9 maps within a chromosomal segment (1q32) 10 and contains … trader joe\u0027s powdered sugar
Bhlhe40 and Bhlhe41 transcription factors regulate alveolar …
WebApr 3, 2024 · BTG2 is a cancer suppressive gene and C-reactive protein treatment could enhance the human monocyte expression of BTG2, which arrests monocytes at G2/M cycle and promotes their apoptosis through p53. 8 BTG2 also regulates mRNA at post-transcriptional level. WebJun 17, 2024 · BACE-1 is required for generating β-amyloid (Aβ) peptides in Alzheimer’s disease (AD). Here, we report that microglial BACE-1 regulates the transition of homeostatic to stage 1 disease-associated microglia (DAM-1) signature. BACE-1 deficiency elevated levels of transcription factors including Jun, Jund, Btg2, Erg1, Junb, Fos, and Fosb in ... WebConsidering the heterogeneity of different cells, we further validated the expression of BTG2 in different immune cells by single cell sequencing, finding that BTG2 expression was highly expressed in NK cells, T cells, B cells, monocytes, macrophages, and neutrophils in the LUAD immune microenvironment. trader joe\u0027s potsticker