Collagen type xxv
WebCollagen alpha-1(XXV) chainis a proteinthat in humans is encoded by the COL25A1gene. [5][6] COL25A1 is a brain-specific membrane-bound collagen. WebHuman ortholog(s) of this gene implicated in congenital fibrosis of the extraocular muscles 5. Orthologous to human COL25A1 (collagen type XXV alpha 1 chain). [provided by Alliance of Genome Resources, Apr 2024] Other designations. collagen alpha-1(XXV) chain, collagen-like Alzheimer amyloid plaque component, procollagen, type XXV, alpha 1
Collagen type xxv
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WebMar 29, 2024 · COL25A1 collagen type XXV alpha 1 chain Gene ID: 84570, updated on 8-Dec-2024 Gene type: protein coding ... CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may … WebOrthologous to human COL25A1 (collagen type XXV alpha 1 chain). [provided by Alliance of Genome Resources, Apr 2024] Col25a1 collagen type XXV alpha 1 chain [ (Norway rat)] Gene ID: 687064, updated on 8-Dec-2024. Summary. Predicted to enable amyloid-beta binding activity; heparin binding activity; and identical protein binding activity. ...
WebThere are eight collagens among the 20 most abundant proteins in the body, which makes these molecules essential building blocks of tissues. In addition, lessons learned from monogenomic mutations in these proteins result in grave pathologies, exemplifying their importance in development. WebMar 29, 2024 · Summary. This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous …
WebDec 24, 2024 · Munezane et al. demonstrate essential roles of muscle-derived collagen XXV in motor axon attraction and intramuscular innervation during development. Collagen XXV interacts with motor axons through its putative receptors PTPσ/δ. Congenital cranial dysinnervation disorder-causing mutations in collagen XXV attenuate the interaction with … WebApr 10, 2024 · Collagen XXV is a transmembrane-type collagen highly transcribed during early myogenesis when primary myofibers form. Limb muscles of E12.5 and E14.5 …
WebJan 22, 2014 · CLAC-P/collagen XXV is a member of the collagen subfamily termed membrane-associated collagens with interrupted triple helices (MACIT), together with type XIII, XVII, and XXIII collagens ( Pihlajaniemi and Rehn, 1995 ). Emerging evidence suggests that MACIT collagens are involved in cell adhesion.
Webcollagen, type XXV, alpha 1 Synonyms 2700062B08Rik Feature Type protein coding gene IDs MGI:1924268 NCBI Gene: 77018 Alliance gene page Transcription Start Sites 6 TSS … farm fresh onions lyricsWebApr 2, 2002 · Both secreted and membrane-tethered forms of CLAC-P/collagen type XXV specifically bound to fibrillized Abeta, implicating these proteins in beta-amyloidogenesis … free pinewood derby car design templatesWebMar 1, 2024 · Type I is found mostly in skin, tendons, ligaments, bones, teeth and between organs. Type II is predominantly located in our eyes and cartilage. Type III is abundant in … free pinewood derby certificate templatesWebCollagen alpha-1 chain is a protein that in humans is encoded by the COL25A1 gene. COL25A1 is a brain-specific membrane-bound collagen. Proteolytic processing releases … free pinewood derby grand prix softwareWebJan 1, 2016 · Type XXV collagen is a 654-aa, brain-specific type II transmembrane protein. The structure comprises an intracellular N-terminal noncollagenous domain (NC1), a … free pinewood derby car templatesWebCollagen, type XXV, alpha 1. COL25A1. Identifiers. Aliases. COL25A1, AMY, CLAC, CLAC-P, CLACP, CFEOM5, Collagen, type XXV, alpha 1, collagen type XXV alpha 1, collagen type … free pinewood derby race excel spreadsheetWebJan 1, 2014 · CLAC-P/collagen XXV is a member of the collagen subfamily termed membrane-associated collagens with interrupted triple helices (MACIT), together with … farm fresh onions