WebApr 12, 2024 · Fibrillin 1 (Fbn1) mutation causes Marfan syndrome (MFS) with thoracic aortic aneurysm (TAA) as the main complication. The mechanisms for extracellular matrix (ECM) homeostasis disruption in MFS TAA are unclear. Here, we found ECM-related gene secreted phosphoprotein 1 (Spp1) increased in Fbn1C1041G/+ mice using transcriptome … WebApr 11, 2024 · In Ads, the gene encoding E1B 55kD, which may inactivate the tumor-suppressor p53 by ubiquitination and keep the virus alive in cells, was deleted in many oncolytic Ads such as H101 and ONYX-015 ...
LncRNA PART1 regulated cell growth, apoptosis and EcM-related genes ...
WebJun 18, 2013 · In SV VSMCs, 1,075 genes were up-regulated and 406 of them were higher than two-fold; 1,399 genes were down-regulated and 424 of them were lower than two-fold as compare with ITA VSMCs.14 ECM-related genes differentially expressed were verificated and listed as following: COL4A4, COL11A1, FN1, TNC, THBS, FBLN, MMP3, … WebMar 24, 2024 · Senescence-related genes were obtained from the CSGene database and analyzed their correlation with the outcome of IPF. A consensus cluster was constructed to classify the samples based on correlated genes. ... ECM deposition can lead to tissue damage and immune cell infiltration, thereby promoting the fibrotic process. For example, ... shivaji death age
Gene Co-Expression Modules as Clinically Relevant Hallmarks of …
WebFeb 28, 2024 · Four ECM-related genes related to overall survival were identified using the Cox regression and LASSO analysis. Then an ECM-related signature was developed and verified in three independent CC cohorts (GSE33882, GSE39582 and GSE29621) from the Gene Expression Omnibus (GEO). A prognostic nomogram was developed incorporating … WebApr 13, 2024 · Cancer-associated fibroblasts (CAFs) play numerous functions in the formation of tumors inside the TME, and related research has shown that CAFs can enhance tumor development in myriads of ways [4 ... WebOct 5, 2024 · In addition, the expression pattern of ECM-related genes by hMSCs on the nanoengineered ECM sheet was altered. Interestingly, the expression of genes for … shivaji death story