WebThe results from 5 patients gave a range of 54 to 173 ng of thioinosinic acid per 5 × 10(6) lymphocytes, with a mean of 110 ng. 4 In an in vitro incubation of azathioprine, 1mM with fresh human blood, 160 and 180 ng of thioinosinic acid per 5 × 10(6) lymphocytes was formed after 0.5 h and 5 h respectively. 5 The assay is suitable for the ... WebSep 1, 1980 · The results from 5 patients gave a range of 54 to 173 ng of thioinosinic acid per 5 x 10(6) lymphocytes, with a mean of 110 ng. 4 In an in vitro incubation of azathioprine, 1mM with fresh human blood, 160 and 180 ng of thioinosinic acid per 5 x 10(6) lymphocytes was formed after 0.5 h and 5 h respectively. 5 The assay is suitable for the study ...
Assay of thioinosinic acid, an active metabolite of ... - Wiley
WebDec 25, 1987 · Abstract. A highly sensitive reversed-phase high-performance liquid chromatographic assay, with ultraviolet detection, for 6-thioinosinic acid and the 6 … WebNov 27, 1992 · The 6-thioguanine nucleotides, 6-thioinosinic acid and 6-methylmercaptopurine metabolites are measured in a single sample. A similar assay measures the parent thiopurine compounds. The limit of quantitation of the assay is 0.03, 0.03 and 0.12 nmol per 8 · 10 8 red blood cells for the 6-thioguanine nucleotides, 6 … dimensions of 480 square feet
Thioinosinic acid CAS#53-83-8 Azathioprine …
WebGet to learn about 6-Thioinosinic acid. The overall knowledge and encyclopedia of 6-Thioinosinic acid covering characteristics, safety, usage, MSDS/SDS and more. Product. Supplier. Encyclopedia. ... For Suppliers. Pharmaceutical Intermediates ... WebNov 27, 1992 · The 6-thioguanine nucleotides, 6-thioinosinic acid and 6-methylmercaptopurine metabolites are measured in a single sample. A similar assay measures the parent thiopurine compounds. The limit of quantitation of the assay is 0.03, 0.03 and 0.12 nmol per 8 x 10(8) red blood cells for the 6-thioguanine nucleotides, 6 … WebA highly sensitive reversed-phase high-performance liquid chromatographic assay, with ultraviolet detection, for 6-thioinosinic acid and the 6-thioguanine nucleotides (6TGNs) was developed. The 6TGNs are major red blood cell metabolites of the immunosuppressive agent azathioprine and the cytotoxic drugs 6-thioguanine and 6-mercaptopurine. fort huachuca aerial view